产品货号：
Z31373
中文名称：
CTCF抗体
英文名称：
Anti-CTCF Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CTCF Antibody |
| 指标别名 | 11 zinc finger protein;CCCTC binding factor;CTCF;CTCFL paralog;Transcriptional repressor CTCF |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | CTCF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human CTCF |
| 实际分子量 | 140KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene.This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains.And this nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins.Depending upon the context of the site,the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor.If the protein is bound to a transcriptional insulator element,it can block communication between enhancers and upstream promoters,thereby regulating imprinted expression.Mutations in this gene have been associated with invasive breast cancers,prostate cancers,and Wilms' tumors.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P49711 |
| 基因名全称 | Transcriptional repressor CTCF |
| 推荐稀释比 | Western blot (WB) 1:500～2000IHC 1:100～1:500 ICC/IF 1:50～1:200 FC 1:50 |
相关搜索：CTCF抗体，CTCF单抗，Anti-CTCF Antibody